Methyl N-Boc-2-morpholinecarboxylate

Methyl N-Boc-2-morpholinecarboxylate - Names and Identifiers

Name	2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester
Synonyms	Methyl N-Boc-2-morpholinecarboxylate methyl 4-Boc-morpholine-2-carboxylate tert-butyl methyl morpholine-2,4-dicarboxylate 4-Boc-Morpholine-2-carboxylic acid Methyl ester 4-(tert-butoxycarbonyl)-2-MethylMorpholine-2-carboxylic acid 2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-met... 4-(tert-Butyloxycarbonyl)morpholine-2-carboxylic acid methyl ester 2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester
CAS	500789-41-3

Methyl N-Boc-2-morpholinecarboxylate - Physico-chemical Properties

Molecular Formula	C11H19NO5
Molar Mass	245.27
Density	1.149±0.06 g/cm3(Predicted)
Boling Point	313.2±42.0 °C(Predicted)
pKa	-2.79±0.40(Predicted)
Storage Condition	2-8°C

Methyl N-Boc-2-morpholinecarboxylate - Introduction

2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester is an organic compound with the chemical formula C14H23NO5. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White solid or crystalline powder.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
-Melting point: about 45-49°C.
-Stability: Stable at room temperature, but avoid exposure to sunlight.

Use:
2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester is commonly used as an intermediate in the chemical field and has many uses:
-Drug research: intermediates used in drug synthesis, which can be used to synthesize various drug compounds.
-Organic synthesis: used as an amide protecting group to prevent the amino group in the amino compound from being attacked by other reactants.
-Chemical labeling: It can be used to label or label other compounds, such as the synthesis of fluorescent probes.

Preparation Method:
The preparation of 2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester can be achieved by the following steps:
1.2,4-morpholinedicarboxylic acid reacts with p-dimethylstyrene (BDME) to generate a diester compound of 2,4-morpholinedicarboxylic acid.
2. The diester is reacted with tert-butyl chloroformate (BOC-Cl) to generate the target compound 2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyyl) 2-methyl ester.

Safety Information:
- 2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester is a chemical and should be operated in an appropriate laboratory environment.
-Contact with skin and inhalation may be harmful to health, should pay attention to protective measures.
-Wear appropriate protective gloves, glasses and lab coats when in use.
-In case of accidental contact or inhalation, seek medical help immediately.

Last Update：2024-04-09 15:17:58